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Glaucoma

Glaucoma is a condition (more accurately, a group of related conditions) where the optic nerve is slowly damaged. The optic nerve connects the eye to the brain and damage caused by glaucoma causes irreversible loss of sight.

The commonest form of glaucoma is called Primary Open Angle Glaucoma (POAG). Typically, POAG causes damage, which initially affects the peripheral vision which is not noticed by the patient. Without treatment, damage may continue slowly, eventually causing loss of central vision with blindness. The whole process from normal sight to blindness can take many years. High eye pressure is the commonest recognized cause of POAG, though about 30% of patients develop glaucoma despite apparently normal eye pressure (Normal Tension Glaucoma, NTG).

Because early glaucoma is symptomless it is usually noted as part of the routine examination undertaken by an optometrist (optician). The optometrist will identify glaucoma by measuring the eye pressure, examining the optic nerve and evaluating the field of vision.

Glaucoma is rare in people under the age of 40. It tends to run in families (though there are many patients who have no recognized history in their family). It is more common in people of Black African/Caribbean descent and in short-sighted people.

Treatment of POAG and NTG depends upon reducing the eye pressure to a level low enough to prevent further damage. We talk of 'target-pressures'; eye pressures at which further damage to the optic nerve is unlikely. Every patient has a different 'target-pressure' which will typically be approximately 30% lower than the eye pressure at which damaged first occurred (the pressure before treatment was started). Initial treatment involves use of eye drops. There are several different glaucoma drops available, which are administered from one to four times a day. Treatment is usually required for life.

Once diagnosed, glaucoma requires long-term follow-up. The frequency of follow-up is dependant upon factors such as the patients' age and severity of disease. Each visit to the doctor involves reviewing treatment, measuring eye pressure, examining the eye and optic nerve and assessing the visual field. If the glaucoma is getting worse treatment will be changed.

Glaucoma surgery is reserved for the minority of patients who do not respond to drop treatment. Surgery may involve lasers (laser trabeculoplasty, laser iridotomy or diode laser) or traditional surgery (trabeculectomy).

Trabeculectomy surgery is usually undertaken under local anaesthetic. Trabeculectomy entails making a small drainage hole into the eye, which allows the fluid within the eye to drain out slowly, thereby reducing pressure. Most trabeculectomy operations reduce eye pressure long-term. Common problems in the short term (1-2 months post surgery) include discomfort, redness, low pressure, high-pressure and reduction in vision. Most operations settle well after this period. Longer-term, a minority of patients can suffer irritation, increase in pressure, low pressure or cataract.

 


Early glaucomatous optic disc cupping 
with haemorrhage

Severe glaucomatous optic disc cupping

 

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